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Sipione Lab | University of Alberta

Simonetta Sipione Laboratory, University of Alberta | Research in our laboratory focuses on Huntington’s disease (HD), an inherited neurodegenerative disorder that causes progressive motor and cognitive dysfunction. Our goal is to understand the cellular and molecular mechanisms underlying this devastating disease and to identify potential therapeutic targets.

http://www.sipionelab.org/

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CONTACTS AT SIPIONELAB.ORG

Simonetta Sipione

9-21 Medic●●●●●●●●●●s Building

Edm●●●ton , Alberta, T6G 2H7

CA

1.78●●●●5885
ss●●●●●●@ualberta.ca

View this contact

Simonetta Sipione

9-21 Medic●●●●●●●●●●s Building

Edm●●●ton , Alberta, T6G 2H7

CA

1.78●●●●5885
ss●●●●●●@ualberta.ca

View this contact

Simonetta Sipione

9-21 Medic●●●●●●●●●●s Building

Edm●●●ton , Alberta, T6G 2H7

CA

1.78●●●●5885
ss●●●●●●@ualberta.ca

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Sipione Lab | University of Alberta | sipionelab.org Reviews
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Simonetta Sipione Laboratory, University of Alberta | Research in our laboratory focuses on Huntington’s disease (HD), an inherited neurodegenerative disorder that causes progressive motor and cognitive dysfunction. Our goal is to understand the cellular and molecular mechanisms underlying this devastating disease and to identify potential therapeutic targets.
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Sipione Lab | University of Alberta | sipionelab.org Reviews

https://sipionelab.org

Simonetta Sipione Laboratory, University of Alberta | Research in our laboratory focuses on Huntington’s disease (HD), an inherited neurodegenerative disorder that causes progressive motor and cognitive dysfunction. Our goal is to understand the cellular and molecular mechanisms underlying this devastating disease and to identify potential therapeutic targets.

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Sipione Lab | University of Alberta

http://www.sipionelab.org/surroundings.asp

University of Alberta constantly ranks in the top four Universities in Canada (best overall in 2006 according to a survey conducted by the Canadian news magazine Maclean s). In 2008 a survey conducted by The Scientist ranked University of Alberta 7th in the top 100 best international Institutions to work for post-doctoral fellows.

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Sipione Lab | University of Alberta

http://www.sipionelab.org/lab.asp

We are located on the 9th floor of the Medical Sciences Building, in the Department of Pharmacology at the University of Alberta. Our laboratory is equipped with state-of-the-art cell culture, biochemistry and molecular biology facilities. Other research cores available to us are:. Lipid analysis facility equipped with HPLC and GC. Cell imaging facility which offers state-of-the-art confocal, spinning disk and two-photon microscopes. Proteomics facility equipped with MALDI-TOF MS/MS. Real-time PCR, RT-PCR.

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Sipione Lab | University of Alberta

http://www.sipionelab.org/people.asp

Simonetta Sipione, PhD. Simonetta Sipione, PhD. Alberta Heritage Foundation for Medical Research Scholar. Canada Research Chair in Neurobiology of Huntington's disease. Bsc In Biology, University of Catania, Italy. PhD In Biochemistry, University of Catania, Italy. Post-graduate specialty in Clinical Biochemistry University of Catania, Italy. Post-doctoral fellow, University of Milano, Italy. Post-doctoral fellow, University of Alberta, Canada. Characterization of HD transgenic mice. Cell signaling in HD.

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Sipione Lab | University of Alberta

http://www.sipionelab.org/default.asp

Research in our laboratory focuses on Huntington's disease (HD), an inherited neurodegenerative disorder that causes progressive motor and cognitive dysfunction. Our goal is to understand the cellular and molecular mechanisms underlying this devastating disease and to identify potential therapeutic targets. Visit the other sections to learn more about us. For being awarded the Queen Elisabeth II Studentship Award! For receiving a travel award from the Canadian Association for Neuroscience.

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Sipione Lab | University of Alberta

http://www.sipionelab.org/publications.asp

Selected publications on Huntington's disease:. Di Pardo A, Maglione V, Alpaugh M, Horkey M, Atwal RS, Sassone J, Ciammola A., Steffan JS, Foud K, Truant R and Sipione S. 2011) Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice. PNAS. Atwal RS, Desmond CR, Caron N, Maiuri T, Xia J, Sipione S. Maglione V, Marchi P, Di Pardo A, Lingrell S, Horkey M, Tidmarsh E and Sipione S. Posse de Chaves E and Sipione S. Dec 17 [Epub ahead of print].

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Sipione Lab | University of Alberta

Research in our laboratory focuses on Huntington's disease (HD), an inherited neurodegenerative disorder that causes progressive motor and cognitive dysfunction. Our goal is to understand the cellular and molecular mechanisms underlying this devastating disease and to identify potential therapeutic targets. Visit the other sections to learn more about us. For being awarded the Queen Elisabeth II Studentship Award! For receiving a travel award from the Canadian Association for Neuroscience.

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