muralab.org

p4b.muralab.org

Mura Lab :: Home

http://www.p4b.muralab.org/index.html

At the University of Virginia. Seeks a deeper understanding of the structure, function/dynamics, and evolution of RNA– and DNA–based protein assemblies. In particular, we are currently investigating ribonucleoprotein (RNP) assemblies built upon scaffolds of Sm proteins, such as the Sm-like archaeal proteins ('SmAP') shown at left, as part of efforts to elucidate questions such as what these protein•••RNA complexes look like at atomic resolution ( structure. Domains of life ( evolution. 2010, Mura Lab.

p4b.muralab.org

Mura Lab :: Philanthropy

http://www.p4b.muralab.org/funding/philanthropy.html

At the University of Virginia. Interested in becoming a benefactor of the Mura Lab? We work in the area of basic ( versus. Mdash; Sm proteins are auto-antigens in autoimmune diseases such as systemic lupus erythematosus and rheumatoid fever; the Sm family also includes a set of cancer-associated Sm proteins ('CaSm'). Mdash; Sm proteins are intimately involved in quorum sensing, biofilms, and bacterial pathogenesis. In the scientific publications that report our results and findings (which we make freely ...

p4b.muralab.org

Mura Lab :: Software

http://www.p4b.muralab.org/software

At the University of Virginia. The following software packages, libraries, utilities, patches, benchmarks, etc. Have been developed in our lab or in collaboration with others, and are freely available:. P4B : Programming for Bioscientists. PaPy : Parallel Pipelines in Python for Distributed Data-processing. ZenCogent : 3D Biomolecular Structure Analysis in PyCogent. PBCTools : VMD plugin for manipulating MD trajectories computed under periodic boundary conditions, particularly for oblique cells. The goal...

p4b.muralab.org

Mura Lab :: Wikis

http://www.p4b.muralab.org/wikis

At the University of Virginia. We host or maintain the following wiki resources:. Mdash; Our main lab wiki. Mdash; A knowledge-base for the Sm protein family. Mdash; Undergrad–level educational initiative. Mdash; Structural biology, Computational biology, Molecular biophysics. Grad–level "methods" series. Mdash; Wiki farm. 2009→present Mura Lab. Design adapted from Viklund. Comments / questions → cmura@virginia.edu.

p4b.muralab.org

Mura Lab :: Gallery

http://www.p4b.muralab.org/gallery

At the University of Virginia. As we try to understand sequence ↔ structure. In the evolutionary context of the RNA-associated Sm protein superfamily. Who do the science. Elsewhere: development sandboxes: pymol. Crystal structure of an Sm-like archaeal protein (SmAP) from Pyrobaculum aerophilum. Crystal structure of Pyrobaculum aerophilum. Truncated octahedral PBCs for MD simulations .of a DNA–binding NFκB dimer. Kappa;B DNA element. Pore of an Sm. After Collin's successful defense; 01may2012. 2009→...

p4b.muralab.org

Mura Lab :: Resources

http://www.p4b.muralab.org/resources

At the University of Virginia. Is a local, Linux-based computing infrastructure that we have developed. We also use UVa's new (Fall 2014) Rivanna. 2009→present Mura Lab. Comments / questions → cmura@virginia.edu.

p4b.muralab.org

Mura Lab :: People

http://www.p4b.muralab.org/people

At the University of Virginia. Collaborators and Other Colleagues. Mura Lab peeps, 18feb2013. Mura Lab peeps, traditional, 13apr2012. Presenting her poster, 12apr2012, Chem Dept poster session. Names link to personal websites). Assistant Professor, Department of Chemistry, University of Virginia. 2008 → present]. Other affiliations: Structural and Computational Biology and Biophysics, UVa Health Sciences;. UVa Cancer Research Center; Biotechnology Training Program; Beckman Scholars mentor;. Ndash;year UV...

p4b.muralab.org

Mura Lab :: Teaching

http://www.p4b.muralab.org/teaching

At the University of Virginia. Lecture– or lab–based courses. Biochemistry Laboratory I (Fa2010, Fa2012. Biochemistry Laboratory II (Sp2010, Sp2012, Sp2013. Advanced Biochemistry I (Fa2008, Fa2009, Fa2010, Fa2014. Advanced Biochemistry II (Sp2016). X-ray Diffraction Series (Fa2013, Fa2014). Molecular Physiology and Biophysics (guest lectures in Sp2009, Sp2010). Biomolecular Structure (guest lectures in Fa2010, Fa2011, Sp2014). Mdash; Programming for Bioscientists. Mdash; Biochemistry Lab Education. UV-VI...