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The Goodin Lab

A Research Laboratory lead by Professor David B. Goodin in the Department of Chemistry, University of California, Davis.

http://www.goodinlab.com/

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The Goodin Lab | goodinlab.com Reviews
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A Research Laboratory lead by Professor David B. Goodin in the Department of Chemistry, University of California, Davis.
<META>
KEYWORDS
1 UC Davis
2 Chemistry
3 David B. Goodin
4 David Goodin
5 heme enzymes
6 structural biology
7 metalloenzymes
8 chemistry
9 biochemistry
10
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ucdavis chemistry home,goodin lab,research,lab members,publications,positions,latest news,davis california,the goodin lab
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The Goodin Lab | goodinlab.com Reviews

https://goodinlab.com

A Research Laboratory lead by Professor David B. Goodin in the Department of Chemistry, University of California, Davis.

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The Goodin Lab

http://www.goodinlab.com/publications.html

The Goodin Lab / Publications. Myers, W.K., Lee, Y.-T., Britt, R. D. and Goodin, D.B. (2013) The Conformation of P450cam in Complex with Putidaredoxin Is Dependent on Oxidation State, J. Am. Chem. Soc 135, 11732. Barelier, S., Boyce, S.E., Fish, I., Fischer, M., Goodin, D.B., and Shoichet, B.K. (2013) Roles for Ordered and Bulk Solvent in Ligand Recognition and Docking in Two Related Cavities, PLoS ONE 8, 69153. Nigro, A.P., and Goodin, D.B. (2010) “Reaction of N-hydroxyguanidine wi...Lee, Y.-T.,...Annal...

2

The Goodin Lab

http://www.goodinlab.com/index.html

Our research is focused on understanding how metalloenzymes operate. We are also working to re-engineer these enzymes to develop novel catalysts. That are capable of oxidizing specific substrates. Our experimental approach involves the integrated use of multidisciplinary techniques including molecular biology, protein engineering, x-ray crystallography, electron paramagnetic resonance, electrochemistry, calorimetry and kinetics. Engineered enzymes may have practical utility as bio-sensors, reagents f...

3

The Goodin Lab

http://www.goodinlab.com/positions.html

The Goodin Lab / News. There are occasional openings for a postdoctoral position in heme enzyme structure and function in the Goodin lab. Multidisciplinary skills are very desirable, from molecular biology apporaches to molecular biology to structural and biophysical techniques including X-ray structure determination, spectroscopy, kinetics and electrochemistry. If interested, please send a letter of introduction and CV to:. Professor David B. Goodin. University of California, Davis. Davis, CA 95616.

4

The Goodin Lab

http://www.goodinlab.com/members.html

David B. Goodin. Davis, CA 95616. Https:/ sites.google.com/site/hellont92. Undergraduate Intern, Biochemistry. John w rosenberg@brown.edu. Prof Stefan Vetter, Ph.D. Boca Raton, FL. David Mandelman, Ph.D. San Diego, CA. Anna-Maria Hays, Ph.D. San Diego, CA. Prof Alycen Nigro, Ph.D. Western CT State Univ. Mark Roach, Ph.D. San Diego, CA. Prof Marc Solioz, Ph.D. Dept of Clin. Pharmacol. University of Berne, Switzerland. Prof Shinichi Ozaki, Ph.D. Inst for Mol. Science. Prof Judy Hirst, Ph.D. Yi Cao, Ph.D.

5

The Goodin Lab

http://www.goodinlab.com/news.html

The Goodin Lab / Research. Recent new results and events. How does P450cam open and close its active site? Here is an experimentally derived animation. Of 21 crystal structures showing a proposed trajectory for opening of the substrate binding channel. A protein based model for nitric oxide synthase. Describes how a peroxidase was used to construct a model for the reactions catalyzed by the second cycle of nitric oxide synthase. P450cam displays an open personality. We have solved the first structure.

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Faculty | Biophysics Graduate Group

http://bph.ucdavis.edu/faculty/index.html

Skip to page content. Secondary navigation and site ownership. The Structure and Mechanisms of Microtubule Regulatory Proteins in Assembly and Disassembly of tubulin dimers. Structure and function of calcium sensor proteins. Structural Biochemistry, Enzymology and Protein Engineering of Protein-nucleic acid Interactions. Structure and function of biologically significant enzymes with redox-active transition metal centers, clusters or organic radicals in their active site. Molecular-to-cellular bioenginee...

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Our research is focused on understanding how metalloenzymes operate. We are also working to re-engineer these enzymes to develop novel catalysts. That are capable of oxidizing specific substrates. Our experimental approach involves the integrated use of multidisciplinary techniques including molecular biology, protein engineering, x-ray crystallography, electron paramagnetic resonance, electrochemistry, calorimetry and kinetics. Engineered enzymes may have practical utility as bio-sensors, reagents f...

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