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GlobPlot 2.3 - Predictor of intrinsic protein disorder & globularity

Intrinsic Protein Disorder, Domain and Globularity Prediction. SwissProt ID or AC:. Sequence (Amino acid single letter IUPAC code):. B-factors 3.5 std.dev (Refer to paper). B-factors 2.0 std.dev (Less stringent). REMARK-465 (Missing X-RAY coordinates). Perform SMART/Pfam domain prediction. Minimum domain length (peak width). Maximum linker length (join distance). 1st derivative Savitzky-Golay frame. 2nd derivative Savitzky-Golay frame. GlobPlot: exploring protein sequences for globularity and disorder.

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GlobPlot 2.3 - Predictor of intrinsic protein disorder & globularity | globplot.embl.de Reviews
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Intrinsic Protein Disorder, Domain and Globularity Prediction. SwissProt ID or AC:. Sequence (Amino acid single letter IUPAC code):. B-factors 3.5 std.dev (Refer to paper). B-factors 2.0 std.dev (Less stringent). REMARK-465 (Missing X-RAY coordinates). Perform SMART/Pfam domain prediction. Minimum domain length (peak width). Maximum linker length (join distance). 1st derivative Savitzky-Golay frame. 2nd derivative Savitzky-Golay frame. GlobPlot: exploring protein sequences for globularity and disorder.
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1 Russell/Linding protein disorder order domain boundaries predictor structural genomics target selection globularity plotter globplot disembl embl intrinsic intrinsically IDPs IDP IUPs IUP prediction loops unstructured unfolded intrinsically proteomics non-globular globular x-ray nmr polypeptides biopolymers IUP IUPs IDP IDPs ELM EL
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GlobPlot 2.3 - Predictor of intrinsic protein disorder & globularity | globplot.embl.de Reviews

https://globplot.embl.de

Intrinsic Protein Disorder, Domain and Globularity Prediction. SwissProt ID or AC:. Sequence (Amino acid single letter IUPAC code):. B-factors 3.5 std.dev (Refer to paper). B-factors 2.0 std.dev (Less stringent). REMARK-465 (Missing X-RAY coordinates). Perform SMART/Pfam domain prediction. Minimum domain length (peak width). Maximum linker length (join distance). 1st derivative Savitzky-Golay frame. 2nd derivative Savitzky-Golay frame. GlobPlot: exploring protein sequences for globularity and disorder.

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1

Licenses for GlobPlot™

http://globplot.embl.de/html/license.html

In terms of licences it is important to distinguish between the web version and the pipeline version as they are covered by different licenses. The web service running at EMBL can be accessed freely by both academia and industry. If, however, you wish to have the GlobPlot web server running locally, you will be required to sign a Material Transfer Agreement. This agreement does not cost any money for academic instutions. Please contact EMBL's Enterprise Management EMBLEM.

2

GlobPlot 2.3 - Predictor of intrinsic protein disorder & globularity

http://globplot.embl.de/cgiDict.py?key=process&amp;SP_entry=PRIO_HUMAN&amp;do_smart=true

Invalid syntax in SwissProt record: none.

3

GlobPlot Links

http://globplot.embl.de/html/links.html

Links to (non-)globular protein internet space. Link to GlobPlot WSDL file. DisEMBL is our neural network based predictor. Predictor from David Jones' lab. Function prediction in non-globular protein space:. The Eukaryotic Linear Motif Resource. Systematic Discovery of In Vivo Phosphorylation Networks. Thesis on disorder and linear motifs. The phd thesis is also there.). Function prediction in globular protein space:. A domain boundary detector. Domain predictor from David Jones' lab.

4

GlobPlot Help

http://globplot.embl.de/html/help.html

Help on using GlobPlot. GlobPlot is a CGI (Common Gateway Interface) based server accessible at http:/ globplot.embl.de, for exploring disorder and globular segments (GlobDoms). By default the server will send the sequence to the public SMART. The web interface is fairly straight forward to use, the user can paste a sequence or enter the SWISS-PROT/SWALL accession (e.g. Or entry code (e.g. Submitting sequences for prediction. The sequence to be predicted must be specified in one of two ways:. To interpre...

5

GlobPlot Help

http://globplot.embl.de/html/propensities.html

These sets are the heart ofGlobPlot, feel free to use them but refer to GlobPlot NAR paper ifyou do! If you need further help please contact Rune Linding.

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LINKS TO THIS WEBSITE

disprot.org disprot.org

Disprot - Database of Protein Disorder

http://www.disprot.org/predictors.php

Xue, B., R. L. DunBrack, R.W. Williams, A.K. Dunker, and V. N. Uversky (2010) "PONDR-Fit: A meta-predictor of intrinsically disordered amino acids." Biochim. Biophys. Acta 1804(4):996-1010. Internal pointer to the PONDR-FIT meta-predictor and other PONDR methods. Linding R, Jensen LJ, Diella F, Bork P, Gibson TJ, Russell RB. "Protein disorder prediction: implications for structural proteomics." Structure. 2003;11(11):1453-9. Dosztanyi Z, Csizmok V, Tompa P, Simon I. "IUPred: web server for the predic...

lindinglab.science lindinglab.science

Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells — Rune Linding : Research Group

http://www.lindinglab.science/news

Only in current section. Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells. Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer treatments. Lori Waters, Waters Biomedical, 2015. Computational Rosetta Stone decodes Mutations Rewiring Cancer Signaling. Lead researcher on the projects, Prof Dr Rune Linding from the Biotech Research and Innovation Cen...

lindinglab.org lindinglab.org

Tony Pawson (1952 - 2013) — Rune Linding : Research Group

http://www.lindinglab.org/news/tony-pawson-1952-2013

Only in current section. Tony Pawson (1952 - 2013). Tony Pawson (1952 - 2013). The entire world-wide research community mourns the passing of Dr Tony Pawson. It is with great sadness that we learned that we have lost our great hero, close friend, fantastic mentor, superb colleague, wonderful human being and maverick of a scientist Tony Pawson. Across biology and life-sciences this will be felt deep and long. There is no field we can imagine that will not be touched by this massive loss. Take care and sta...

lindinglab.org lindinglab.org

Links — Rune Linding : Research Group

http://www.lindinglab.org/links

Only in current section. Links to other laboratories, useful tools and databases, institutional units. Doug Lauffenburger : Research Group. Department of Biological Engineering Massachusetts Institute of Technology (MIT). Laboratory of Norbert Perrimon, Ph.D. Department of Genetics Harvard Medical School Howard Hughes Medical Institute. Institute of Molecular Life Sciences University of Zurich. Lunenfeld-Tanenbaum Research Institute Mount Sinai Hospital. Simple Modular Architecture Research Tool.

lindinglab.org lindinglab.org

Publications — Rune Linding : Research Group

http://www.lindinglab.org/Publications

Only in current section. Here, we provide all our research publications and related information, including web-services and supplements. Linding Lab, BRIC [2014-present]. Publications from our group at the Biotech Research and Innovation Center (BRIC), University of Copenhagen (UCPH). Linding Lab, DTU [work from 2011-2014]. Publications of the Cellular Signal Integration Group (C-SIG), Center for Biological Sequence Analysis (CBS), Department of Systems Biology, Technical University of Denmark (DTU).

lindinglab.org lindinglab.org

Press — Rune Linding : Research Group

http://www.lindinglab.org/press

Only in current section. Press releases related to our research. KU-forskere slår igennem med banebrydende kræftforskning. GENNEMBRUD - Det anerkendte tidskrift CELL hylder KU-forskning i spritny publikation. Resultaterne kan ændre måden vi undersøger og behandler kræftpatienter på, siger laboratorieleder. Using Proteomics to Understand How Genetic Mutations Rewire Cancer Cells. University of Copenhagen (UCPH) and Beckman Coulter Genomics (BCG) Collaborate to Unravel How Mutations Rewire Cancer Cells.

lindinglab.org lindinglab.org

Rune Linding : Research Group

http://www.lindinglab.org/accessibility-info

Only in current section. This site uses the Open Source Content Management System Plone. And has been designed to be completely accessible and usable, working in accordance with the Web Content Accessibility Guidelines (. V10) If there is anything on this site — accessibility or validation related — that is not according to the standard, please contact the Site Administration. And not the Plone Team. Access keys are a navigation device enabling you to get around this web site using your keyboard. Are sub...

lindinglab.org lindinglab.org

Funding — Rune Linding : Research Group

http://www.lindinglab.org/funding

Only in current section. We gratefully acknowledge support from the following agencies. Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells. Sep 17, 2015. Enzyme paves the way for the spread of cancer cells to bones. May 27, 2015. Linding Lab moves to BRIC@UCPH. Jul 31, 2014. Tony Pawson (1952 - 2013). Aug 11, 2013. Navigating cancer network attractors for tumor-specific therapy. Sep 16, 2012. August 2016 ». Powered by Plone and Python.

lindinglab.org lindinglab.org

Photos — Rune Linding : Research Group

http://www.lindinglab.org/photos

Only in current section. Fish Creek Falls, Steamboat Springs, CO, USA. From left to right (top to bottom): Rune Linding, James Longden, Franziska Völlmy, Xavier Robin, Jinho Kim, Jesper Ferkinghoff-Borg, Craig Simpson and Mathias Engel. Summer 2013 - Enroute to Volcano Hekla, Selfoss, Iceland. Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells. Sep 17, 2015. Enzyme paves the way for the spread of cancer cells to bones. May 27, 2015. Linding Lab moves to BRIC@UCPH. Jul 31, 2014.

lindinglab.org lindinglab.org

Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells — Rune Linding : Research Group

http://www.lindinglab.org/news

Only in current section. Digital ‘Rosetta Stone’ Decrypts How Mutations Rewire Cancer Cells. Scientists have discovered how genetic cancer mutations systematically attack the networks controlling human cells, knowledge critical for the future development of personalized precision cancer treatments. Lori Waters, Waters Biomedical, 2015. Computational Rosetta Stone decodes Mutations Rewiring Cancer Signaling. Lead researcher on the projects, Prof Dr Rune Linding from the Biotech Research and Innovation Cen...

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GlobPlot 2.3 - Predictor of intrinsic protein disorder & globularity

Intrinsic Protein Disorder, Domain and Globularity Prediction. SwissProt ID or AC:. Sequence (Amino acid single letter IUPAC code):. B-factors 3.5 std.dev (Refer to paper). B-factors 2.0 std.dev (Less stringent). REMARK-465 (Missing X-RAY coordinates). Perform SMART/Pfam domain prediction. Minimum domain length (peak width). Maximum linker length (join distance). 1st derivative Savitzky-Golay frame. 2nd derivative Savitzky-Golay frame. GlobPlot: exploring protein sequences for globularity and disorder.

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