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Eporgen - Nurturing the winners

Eporgen is the first Italian company, entirely funded by private, non-institutional investors, which is dedicated to seed capital investments in the area of life sciences.

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Eporgen - Nurturing the winners | eporgen.com Reviews
<META>
DESCRIPTION
Eporgen is the first Italian company, entirely funded by private, non-institutional investors, which is dedicated to seed capital investments in the area of life sciences.
<META>
KEYWORDS
1 Eporgen
2 portfolio
3 start-up
4 patents
5 bio
6 financing
7 pharma
8 research
9 academic institutions
10 proof-of-concept
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about us,apavadis,bionucleon,genovax,glyconova,rotalactis,spider biotech,target heart biotec,technologies,biopaint,narvalus,notopharm,smile biotech,people,press room,factsheet,intranet,designed by
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Eporgen - Nurturing the winners | eporgen.com Reviews

https://eporgen.com

Eporgen is the first Italian company, entirely funded by private, non-institutional investors, which is dedicated to seed capital investments in the area of life sciences.

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eporgen.com eporgen.com
1

About Eporgen Venture

http://www.eporgen.com/about.asp

Eporgen commenced operations in 2005 and is based in the Silvano Fumero Bioindustry Park. Close to Ivrea in the Piedmont region of Italy. With about 20 staff in total, Eporgen and its start-up companies operate an efficient business model that combines aspects of a venture capital and a virtual pharma company and relies on a network of scientific advisors, contract research organisations and academic institutions. VAT 08982780010 BioIndustry Park Silvano Fumero - Via Ribes 5, 10010 Colleretto Giacosa (TO).

2

Eporgen - Nurturing the winners

http://www.eporgen.com/aziende/rotalactis.asp

Originated from the National Research Council and the University of Torino; established in 2008, it operates in the area of nutraceuticals. One patent filed in 2010. Identification and isolation of lactadherin with anti-rotavirus activity from the proteins associated with the fat globules in equine (donkey) milk. Complete amino-acid sequencing of the equine lactadherin protein has been accomplished. Peptides derived from equine lactadherin with anti-rotavirus activity have been identified and an in vitro.

3

Where is Eporgen. Contact Us

http://www.eporgen.com/where.asp

Eporgen S.p.A. C/o Silvano Fumero Bioindustry Park. Via Ribes, 5. 10010 Colleretto Giacosa (TO). Tel 39 0125 561000. Fax 39 0125 538791. E mail: info@eporgen.com. Eporgen is searching for suitable partners for collaborations and out- licensing of projects within its portfolio of start-up companies. To discuss potential opportunities, please contact us at the following e mail address: info@eporgen.com. In una mappa di dimensioni maggiori. 390125.561000 - Fax.

4

Eporgen - Nurturing the winners

http://www.eporgen.com/aziende/spiderbiotech.asp

Originated from the University of Siena; established in 2005, it operates in the field of anti-infectives. Two patents filed in 2008 and 2009. Selected publications for antibacterial program:. Synthesis, characterization, antimicrobial activity and LPS-interaction properties of SB041, a novel dendrimeric peptide with antimicrobial properties , Bruschi et al. 2010) Peptides, 31. Link: http:/ www.ncbi.nlm.nih.gov/pubmed/20438783. 2007) Nanomedicine, 3. Selected publications for antiviral program:. Interest...

5

Glyconova

http://www.eporgen.com/aziende/glyconova.asp

Established in 2009 by Dr. Ghiselli, a former Professor of Pathology and Cellular Biology at the Thomas Jefferson University of Philadelphia (U.S.A.); it operates in the fields of glycobiology and anti-cancer drug discovery. GLCE has been validated as a target for the development of anti-tumor agents. Completed a medicinal chemistry program where 1,500 molecules have been screened and 30 hits, belonging to different chemical families, identified to date. 390125.561000 - Fax.

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thbiotec.com thbiotec.com

Target Heart Biotech - Melusin structure and expression

http://www.thbiotec.com/melusin.asp

Melusin structure and expression. Click on the figure to enlarge. Is a protein selectively expressed in skeletal muscle and heart, and binding to the beta1 integrin cytoplasmic domain ( Brancaccio et al., 1999. Primary amino acidic sequence of melusin ( Fig. 2. Revealed the presence of two cysteine/histidine rich domains capable of binding Zn2 known as CHORD domains at the N-terminal portion of the protein (red globules). However, when heart is exposed to conditions of chronic pressure overload, such as ...

thbiotec.com thbiotec.com

Target Heart Biotech Business Development

http://www.thbiotec.com/business.asp

TH s mission is to exploit the unique properties of melusin towards the development of novel therapies:. The effects on the contractile power of the heart may have therapeutic applications in various heart failure conditions (eg treatment of patients with severe heart failure such as NYHA classes 3-4) as well as in pulmonary arterial hypertension. The other cardioprotective effects of melusin have various applications. TH is open to various ways of partnership that include any of its projects:.

thbiotec.com thbiotec.com

Target Heart Biotech selected publications

http://www.thbiotec.com/literature.asp

Selected publications on melusin. Brancaccio M., Guazzone S., Menini N., Sibona E., Hirsch E., De Andrea M., Rocchi M., Altruda F., Tarone G., Silengo L. Melusin is a new muscle-specific interactor for beta(1) integrin cytoplasmic domain. J Biol Chem - 1999 Oct 8; 274(41):29282-8. Brancaccio M., Fratta L., Notte A., Hirsch E., Poulet R., Guazzone S., De Acetis M., Vecchione C., Marino G., Altruda F., Silengo L., Tarone G., Lembo G. Nat Med - 2003 Jan; 9(1):68-75. Nat Med. - 2003 Jan; 9(1):19-20. Sbroggiò...

thbiotec.com thbiotec.com

Target Heart Biotech S.r.l.

http://www.thbiotec.com/default.asp

Target Heart Biotec (TH) is a spin-off from the University of Turin, Italy. It is a virtual company that operates in the cardiovascular field and belongs to the portfolio of Eporgen Venture. TH discovered the muscle-specific protein melusin. R-h melusin) has been manufactured, characterised and its therapeutic activity has been demonstrated in a pressure overload mouse model. TH is now seeking partnerships. To develop r-h melusin towards its various therapeutic applications.

thbiotec.com thbiotec.com

Contact Target Heart Biotech

http://www.thbiotec.com/where.asp

Target Heart Biotech S.r.l. C/o Silvano Fumero Bioindustry Park. Via Ribes, 5. 10010 Colleretto Giacosa (TO). VAT Reg No: 09161530010. Tel 39.0125.561000. Fax 39.0125.538791. E mail: gtarone@thbiotec.com. Visualizza Target Heart Biotech. In a larger map. Target Heart Biotech S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

thbiotec.com thbiotec.com

Target Heart Biotech Literature

http://www.thbiotec.com/patents.asp

Target Heart Biotech s patents:. Melusin, a muscle specific protein, as a drug target for prevention and treatment of heart failure. Filed by the University of Turin, with priority date in December 2002; Target Heart has the global, exclusive rights to this patent. The patent has been granted in the US, Europe and Canada; EP15753534B1; USA 7,531,714; CA 2740237). Recombinant melusin fusion protein as pharmacological agent in the treatment of heart pathologies and compositions thereof.

thbiotec.com thbiotec.com

Target Heart Biotech Technology & Products

http://www.thbiotec.com/products.asp

TH has discovered the muscle-specific protein melusin. Using genetically modified animals and animal models, TH has collected compelling evidence of the various beneficial effects of melusin on the heart muscle against different stress factors. Recombinant human melusin (r-h melusin) has been manufactured, characterised and successfully reached pre-clinical proof of concept in a pressure overload mouse model. Target Heart Biotech S.r.l. BioIndustry Park Silvano Fumero.

bionucleon.com bionucleon.com

About BioNucleon S.r.l.

http://www.bionucleon.com/about.asp

BioNucleon was founded in June 2005 by Enrico Bucci, Roberto Sapio and Margherita Valente. It has been incubated by Eporgen Venture in the Silvano Fumero Bioindustry Park. Close to Ivrea in the Piedmont region of Italy, while its registered office was kept in Naples. BioNucleon won the Best Young and Innovative Italian Company award of Unioncamere (Association of Italian Chambers of Commerce) in 2006. Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

bionucleon.com bionucleon.com

Bionucleon Literature

http://www.bionucleon.com/literature.asp

Inhibition of HRP-3 using modified oligonucleotides. By E Bucci et al, International patent PCT/ET 2009/004186, filed in 2008. Method for sequence determination of nucleic acids and analogs. By E Bucci et al, Italian patent MI2005A001050, filed in 2005. Link to "Selected publications on HDGF and HPR-3". Bionucleon S.r.l. BioIndustry Park Silvano Fumero. Via Ribes 5, 10010 Colleretto Giacosa (TO).

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Eporgen - Nurturing the winners

Eporgen is the first Italian company, entirely funded by private, non-institutional investors, which is dedicated to seed capital investments in the area of life sciences. The current portfolio of Eporgen is constituted of eleven start-up companies, with innovative early stage therapeutics and diagnostics that cover diverse disease areas (oncology, anti-infectives, cardiovascular), approaches (small molecules, proteins, peptides, vaccines) and technology applications! 390125.561000 - Fax.

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