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EPASG | New Life for Old Antibiotics

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. ESCMID PK/PD of Anti-Infectives Study Group (EPASG). This website serves as a knowledge hub of old antibiotics and will be continuously updated as new data become available. This project is managed by Ursula Theuretzbacher. 2 February, 2014 at 1:20 pm. Excellent website – congratulations to Ursula! 2 February, 2014 at 7:22 pm. 15 April, 2014 at 10:21 am.

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EPASG | New Life for Old Antibiotics | epasg.escmid.org Reviews

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EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. ESCMID PK/PD of Anti-Infectives Study Group (EPASG). This website serves as a knowledge hub of old antibiotics and will be continuously updated as new data become available. This project is managed by Ursula Theuretzbacher. 2 February, 2014 at 1:20 pm. Excellent website – congratulations to Ursula! 2 February, 2014 at 7:22 pm. 15 April, 2014 at 10:21 am.

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1 epasg

2 escmid

3 disclaimer

4 old antibiotics

5 background info

6 reviving

7 availability

8 colistin availability

9 colistin

10 pk of colistin

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epasg,escmid,disclaimer,old antibiotics,background info,reviving,availability,colistin availability,colistin,pk of colistin,dosing of cms,pk/pd of colistin,resistance,breakpoints of colistin,safety of colistin,colistin terminology,composition of colistin

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EPASG | New Life for Old Antibiotics | epasg.escmid.org Reviews

https://epasg.escmid.org

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. ESCMID PK/PD of Anti-Infectives Study Group (EPASG). This website serves as a knowledge hub of old antibiotics and will be continuously updated as new data become available. This project is managed by Ursula Theuretzbacher. 2 February, 2014 at 1:20 pm. Excellent website – congratulations to Ursula! 2 February, 2014 at 7:22 pm. 15 April, 2014 at 10:21 am.

INTERNAL PAGES

epasg.escmid.org

1

Dosing of CMS | EPASG

http://epasg.escmid.org/old-antibiotics/colistin/dosing-of-cms

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. PK and PK/PD studies (Plachouras et al) have been validated in the critical care setting. A higher dosing than originally thought and advised in the product information for the old drug colistin. 1 Mill IU is equivalent to 30 mg of CBA. A correlation of dose and mortality shown by a stepwise decrease in mortality associated with increasing daily colistin dose highlights the importance of adequate dosages. The mortality associated with 3 Mi...

2

Colistin availability | EPASG

http://epasg.escmid.org/old-antibiotics/availability/colistin-availability

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. Colistimethate is widely available. In European countries. Fifteen companies distribute intravenous colistin products in one or several European countries whereas one company produces the active pharmaceutical ingredient and finished dosage forms as lyophilized and dry-filled vials. Colistin products for injection or infusion are available with strength of one and/or two Million International Units (U. Theuretzbacher 2013).

3

Resistance | EPASG

http://epasg.escmid.org/old-antibiotics/colistin/resistance

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. And occurence of various infections with colistin-resistant Gram negative bacteria has been shown in a Greek study. 35% of clinical strains of. G Lamprini et al ECCMID 2011. Similarly, in Italy 36% of carbapenem-resistant K. pneumoniae were also colistin-resistant. The high rate of resistance to colistin that was independently associated with worse outcome in this study ( A Capone et al. 2012. Caused by selective pressure due to excessive and ...

4

Prato Consensus 2013 | EPASG

http://epasg.escmid.org/old-antibiotics/colistin/prato-consensus-2013

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. Over the last several years, substantial progress has been made in carrying colistin through procedures equivalent to modern drug development, thereby increasing understanding on how to optimise their clinical use. In view of the recent advances that have occurred, the 1. International Conference on Polymyxins. A key aspect of the program. Which summarizes high-priority areas requiring attention (R. Nation 2013, submitted for publication).

5

Fosfomycin iv | EPASG

http://epasg.escmid.org/old-antibiotics/fosfomycin-iv

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. In contrast to the oral fosfomycin trometamol products, the intravenous formulation is not widely available and “redeveloping” of this last resort antibiotic is not a priority. Hardly any PK/PD studies. Dosage recomendations of fosfomycin in European product informations (SPC). Breakpoint applies to a dosage of 4-8 g x 3. Fosfomycin is well tolerated and it is not clear how much the dose could be increased, especially in patients with volu...

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escmid.org

ESCMID: EPASG

https://www.escmid.org/research_projects/study_groups/pkpd_of_anti_infectives

You may read about the benefits of an ESCMID membership and sign up online. You also find information on ESCMID’s organizational structure of, partnerships with other organizations as well as the society s bylaws. Find out more about ESCMID s study groups and collaborative projects such as EUCAST and EUCIC, ESCMID conferences as well as our Fighting Resistance. Collaborative Centres and Observerships. Trainee Association of ESCMID. Jobs in CM and ID. EU calls and other funding. EOPs for Study Groups.

theuretzbacher.wordpress.com

Leadership of International Societies | Ursula Theuretzbacher, Ph.D.

https://theuretzbacher.wordpress.com/leadership

Ursula Theuretzbacher, Ph.D. Infectious disease scientist – Anti-infective R&D and clinical practice strategies. Leadership of International Societies. Upcoming Conferences and Presentations. Conference and Presentation Archive. Leadership of International Societies. In addition to providing senior level scientific expertise, I participate in the executive direction and project management of highly regarded international anti-infective scientific organizations:. ESCMID PK/PD Study Group ( EPASG. As found...

aida-project.eu

AIDA project - News

http://www.aida-project.eu/news

Friday, 19 August 2016. The Netherlands, Switzerland, Austria, Italy, Sweden, Denmark, France, Poland. The European Commission, DG Research and Innovation, granted an extension of 12 month to the AIDA project that will be completed November 2017. The ASM MICROBE conference (former ASM Annual Meeting ICAAC) took place on June 18-21 in Boston. Mical Paul gave two presentations:. Colistin monotherapy is still a viable option for treatment of MDE-GNB. Controversies in antimicrobial stewardship. Will take pla...

aida-project.eu

AIDA project - Information

http://www.aida-project.eu/back-ground-information/information

Friday, 19 August 2016. The Netherlands, Switzerland, Austria, Italy, Sweden, Denmark, France, Poland. In this section you will find various information about the AIDA drugs as well as general information related to the project. The interest in colistin is still increasing. This trend is apparent when looking at the program of this year's ICAAC. Numerous studies will be presented at ICAAC in Washington DC, Sept 2014. This file lists important colistin presentations. By AIDA partner U. Theuretzbacher ...

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EPASG | New Life for Old Antibiotics

EPASG – NEW LIFE FOR OLD ANTIBIOTICS. PK/PD of fosfomycin iv. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. EPASG – NEW LIFE FOR OLD ANTIBIOTICS. ESCMID PK/PD of Anti-Infectives Study Group (EPASG). This website serves as a knowledge hub of old antibiotics and will be continuously updated as new data become available. This project is managed by Ursula Theuretzbacher. 2 February, 2014 at 1:20 pm. Excellent website – congratulations to Ursula! 2 February, 2014 at 7:22 pm. 15 April, 2014 at 10:21 am.

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