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dna.leeds.ac.uk

dna@leeds

Human genetics research in Leeds.

http://dna.leeds.ac.uk/

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dna@leeds | dna.leeds.ac.uk Reviews
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Human genetics research in Leeds.
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1 autozygosity
2 SNP
3 consanguinity
4 gene mapping
5 autosomal recessive
6 genetic disease
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dna@leeds | dna.leeds.ac.uk Reviews

https://dna.leeds.ac.uk

Human genetics research in Leeds.

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dna.leeds.ac.uk dna.leeds.ac.uk
1

Genetics utilities

http://dna.leeds.ac.uk/utilities

Calculates coefficients of inbreeding from pedigrees (including extraction of pedigree data from Cyrillic files). Decode2Affy, Illumina2Affy and PLink2Affy. Converts deCode, Illumina and PLink genotype data files to an Affymetrix-style format for use by AutoSNPa. Candidate gene prioritisation based on gene expression profiles. Calculates the quality of the sequence in an electropherogram file. Centre for Autozygosity Mapping. Software for genetic mapping using SNP arrays.

2

Sequence analysis programs

http://dna.leeds.ac.uk/sequencing

Here are links to a number of Windows software packages for sequencing or related applications requiring analysis of capillary electropherograms. They have been written by Ian Carr. Is designed to speed up the characterisation of mammalian CpG islands by aligning DNA sequences from bisulphite-modified DNA to the genomic sequence of the CpG island. While simple in principle, this is a tedious error-prone task when done manually. CpGviewer web page. Is an applications designed to analyse the melt curve dat...

3

Genetic mapping programs

http://dna.leeds.ac.uk/autozygosity

Here are links to a number of Windows programs for genetic mapping using autozygosity or other approaches, that have been written by Ian Carr. Finds the genotyping error rate and 'Nocall' genotype rate for Affymetrix microarray SNP chip genotype data. Affymetrix Error Rate web page. Is part of the Agile suite. Or a tab delimited text file formatted as described in the user guide webpage. AgileVariantMapper web page. While it doesn't duplicate the functions of Phaser. Displays autozygous regions from mult...

4

Agile analysis of clonal sequence data

http://dna.leeds.ac.uk/agile

Desktop programs for analyzing massively parallel sequence data. Suite of programs allows the rapid analysis of clonal sequencing data, aligned to the human genome, with a view to identifying disease-causing sequence variants. It comprises several component programs, each with its own user guide and download page, as described below:. Variant that causes congenital cataract, corneal opacity, and glaucoma ( citation. Fastq and Fasta file manipulation and read quality filtering. Displays autozygous regions...

5

NGS Facility

http://dna.leeds.ac.uk/genomics

Next Generation Sequencing Facility. The NGS facility is wholly owned and run by the University of Leeds. And aims to provide a very flexible sequencing service in which cutting edge methodologies can be rapidly developed and provided as a service to both internal and external users. A short video describing the facility can be found here. This machine can generate 600 Gb of data per run and is suitable for a wide range of sequencing application. Read more. We have considerable expertise in analysis of l...

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dna.leeds.ac.uk dna.leeds.ac.uk

dna@leeds

These pages offer access to a variety of software packages for genomic analysis and related tasks in human genetics. They have been developed with the goal of maximizing easy access to powerful data manipulation and analysis methods, by researchers and clinicians who are not necessarily already skilled in bioinformatics. These programs fall loosely into the following categories:. Programs for genetic mapping, including autozygosity mapping of recessive disease genes using SNP arrays.

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Macrogen Online Sequencing Order System

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