ppsp.biocuckoo.org
Welcome to use PPSP system
Prediction of PK-Specific Phosphorylation Site. Tips for using PPSP. 1please use 20 letters for common amino acids. 2both upper and lower cases are acceptable. 3spaces and returns in sequence are allowable. 4for fasta format, the first line should begin with ' '. 5FASTA format is required when mutliple sequences are submitted at one time. Other Phosphorylation Site Prediction Tools and Resources:. 1 Enter the sequence. Predict by all kinases. Predict by individual kinase below Group Info.
pps.biocuckoo.org
PPS 1.0 - PTMs Peptide Scanner
Met and Ace. Regulators. Last update: Apr. 1st, 2018. Diella, et al., 2004. Diella, et al., 2008. And UniProt ( Boutet, et al., 2007. Have been developed to contain PTM information of proteins. However, these annotations are usually not integrated. Moreover, due to the diversity and heterogeneity of protein names, it's difficult to fully obtain the known PTM information for a given protein, by database searching. In this work, we developed a novel software of PTMs Peptide Scanner (PPS). Taken together, w...
phossnp.biocuckoo.org
PhosSNP 1.0 - Influence of protein phosphorylation by nsSNP
Met and Ace. Regulators. Last update: Aug. 10th, 2012. As we are entering the age of Personal Genomics. It has been expected that the knowledge of human genetic polymorphisms and variations could provide a foundation for understanding differences in susceptibility to diseases and designing individualized therapeutic treatments ( Cargill,. Recent progresses of the International HapMap Project and similar projects ( International HapMap Consortium, 2005. And single nucleotide polymorphisms (SNPs) ( Hinds,.
nbapalm.biocuckoo.org
:::NBA-Palm - Prediction of Palmitoylation Site Implemented In Naive Bayesian Algorithm:::
Also known as S-acylation, is one of the most ubiquitous post-translational modifications (PTM), reversibly attaching a 16-carbon saturated fatty acid as lipid palmitate (C16:0) to cysteine residues in protein substrates through thioester linkage ( Bijlmakers and Marsh, 2003. Dietrich and Ungermann, 2004. El-Husseini Ael and Bredt, 2002. Linder and Deschenes, 2003. Smotrys and Linder, 2004. Huang and El-Husseini, 2005. Zhou, et al., 2004. Clark, et al., 2004. Navarro-Lerida, et al., 2004. These intrinsic...
microkit.biocuckoo.org
MiCroKiTS - An Integrated Database of Midbody, Centrosome, Kinetochore, Telomere and Spindle
Met and Ace. Regulators. Last update: Apr. 1st, 2018. 8251; MiCroKiTS INTRODUCTION:. During cell cycle, numerous proteins temporally and spatially localized in distinct sub-cellular regions including centrosome. In budding yeast), kinetochore. Related or homolog structures in plants and budding yeast called as phragmoplast. And five animals, including. Based on the rationale of Seeing is believing ( Bloom K. Then the integrated and searchable database M. Please search the M. MiCroKit 3.0: an integrat...
gps.biocuckoo.org
GPS 3.0 - Kinase-specific Phosphorylation Site Prediction
Met and Ace. Regulators. Last update: Mar. 1st, 2018. Computational prediction of phosphorylation sites with their cognate protein kinases (PKs) is greatly helpful for further experimental design. Although 10 online predictors were developed, the PK classification and control of false positive rate ( FPR. Software was implemented in JAVA and could predict kinase-specific phosphorylation sites for 408. Recently, we released GPS 3.0. With novel Peptide Selection. Human PKs in hierarchy. This website is lin...
dog.biocuckoo.org
DOG 2.0 - Protein Domain Structure Visualization
Met and Ace. Regulators. Last update: Feb. 26th, 2014. Schematic diagram of protein domain structures with functional motifs/sites is an important part in a large proportion of scientific articles which are focused on molecular and cellular researches. In order to estimate how many papers will contain protein domain graphs, we simply chose five typical molecular and cellular magazines, including. The Journal of Cell Biology. Molecular Biology of the Cell. Molecular and Cellular Biology.
csspalm.biocuckoo.org
CSS-Palm - Palmitoylation Site Prediction
Met and Ace. Regulators. Last update: Mar. 1st, 2018. As a special class of post-translational modifications (PTMs), numerous proteins could be covalently modified by a variety of lipids, including myristate (C14), palmitate (C16), farnesyl (C15), geranylgeranyl (C20) and glycosylphosphatidylinositol (GPI), etc ( Casey, 1995. Nadolski and Linder, 2007. Although most of lipid modifications are irreversible, protein S-palmitoylation. Dietrich and Ungermann, 2004. El-Husseini Ael and Bredt, 2002. During the...
ccd.biocuckoo.org
GPS-CCD 1.0 - Computational Predictioin of Calpain Cleavage Sites
Met and Ace. Regulators. Last update: Mar. 1st, 2018. Calpains constitute an important family of the Ca2 -dependent cysteine proteases, which contain a nucleophilic cysteine in the catalytically active site ( Goll. Calpains are widely expressed in mammalians and conserved across eukaryotes ( Futai. For instance, in budding yeast, at least one calpain-like protease, Rim13/Cpl1, has been identified, although its functions are still elusive ( Hayashi. Although many studies have tried to dissect the regulato...
bdmpail.biocuckoo.org
:::PAIL - Prediction of Acetylation on Internal Lysines:::
Protein acetylation is a widespread covalent modification in eukaryotes, transferring acetyl groups from acetyl coenzyme A (acetyl CoA) to either α-amino (N. Group of amino-terminal residues or to the ε-amino group (N. Of internal lysines at specific sites ( Glozak,MA. Kouzarides,T, 2000. Yang,XJ, 2004. As one of the most ubiquitous protein modifications, approximately 85% of eukaryotic proteins are N. Lysine acetylation is less common, but probably more important. N. DNA repair ( Murr,R. Acetylation may...
